Study Purpose/Description
MeTeOR2 is a randomised controlled trial comparing meniscal allograft transplant surgery to personalised knee therapy in people with pain and/or functional limitations post partial meniscectomy (surgery to remove knee cushioning cartilage).
The study aims to identify if one treatment is superior to another for pain and self-reported functioning.
The meniscus is an important structure within the knee. One of its key roles is to cushion impact and protect the gliding surface of the joint from wear. Patients that have damaged their meniscus, and had a removal of the meniscus (a total meniscectomy), are more likely to develop persistent pain after this resulting in years of disability.
At present, there are several treatment options ranging from knee therapy (physiotherapy) to a replacement meniscus also known as a ‘meniscal transplant’. Meniscal transplant is thought to provide cushioning to the joint surfaces and improve symptoms but it has a long recovery period and the operation carries risk of surgery as well as not helping with symptoms. At present, there is no direct evidence that meniscal transplant is better or worse, than a specific targeted rehabilitation and therapy program.
What’s involved?
If you are eligible for the study and consent to participate, you will have a 50% chance of being randomised into one of the two groups.
The first group will receive a meniscal allograft transplant surgery. This surgery involves the implantation of a meniscus which has been procured from a deceased person.
The second group will receive personalised knee therapy. This will involve an assessment of your knee and functioning, and the prescription of a treatment plan tailored to your needs based on the assessment.
How to take part?
If you are interested and think you might be eligible, you can email the researchers at meteor2.study@sydney.edu.au or visit the study webpage
